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This suggests their presence may potentially act as biomarkers for multicentric lymphoma, which are indicators of what’s going on in a cell at a given time. Multicentric lymphoma accounts for approximately 80% to 85% of lymphomas in canine. The signs of lymphoma in canines aren’t always the same, which might make it tough to diagnose at first. There are greater than 30 several varieties of identified canine lymphomas, all of which vary in aggressiveness, survival rates, and medical signs.